jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2011-3-1-6-13jofin-4Research ArticleОбзорыReviewРЕГУЛЯТОРНЫЕ Т-ЛИМФОЦИТЫ В ИММУННОМ ОТВЕТЕ НА ИНФЕКЦИЮRegulatory t cells in immune response to infectionЖелезниковаГ. Ф.ZheleznikovaG. F.

руководитель отдела клинической лабораторной диагностики Научно-исследовательского института детских инфекций, д.м.н., профессор

zheleznikova.galina@gmail.comНаучно-исследовательский институт детских инфекций ФМБА России, Санкт-ПетербургРоссияResearch Institute of Children Infections, FMBA of Russia, Saint-PetersburgRussian Federation20110109201431613Copyright © Железникова Г.Ф., 20142014Железникова Г.Ф.Zheleznikova G.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/4

Обзор содержит современные сведения о регуляторных Т-лимфоцитах (Treg), контролирующих воспалительные реакции и специфический иммунный ответ на внедрение инфекции. Описаны разновидности регуляторных Т-клеток, механизмы их активации и воздействия на клетки-мишени. Подчеркивается двойственная роль Treg в патогенезе инфекций.

The revue includes the contemporary information about regulatory T cells (Treg), that regulate the inflammatory responses and adaptive immune response in defense against infection. The different populations of Treg are described, their activation mechanisms, and the mechanisms of influencing target cells. The double role of Treg in infection pathogenesis is emphasized.

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The authors declare that there are no conflicts of interest present.