jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2015-7-1-18-25jofin-369Research ArticleОбзорыReviewВертикальная передача гепатита В: опасности реальные и мнимыеVertical transmission of hepatitis B: the real and imaginary dangerБелопольскаяМ. А.BelopolskayaM. A.

врач-инфекционист Клинической инфекционной больницы им. С.П. Боткина, к.м.н.; тел.: 8(812)717-47-51

belopolskaya.maria@yahoo.comКлиническая инфекционная больница им. С.П. Боткина, Санкт-Петербург, РоссияРоссияClinical Infectious Diseases Hospital named after S.P. Botkin, Saint-Petersburg, RussiaRussian Federation201508042015711825Copyright © Белопольская М.А., 20152015Белопольская М.А.Belopolskaya M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/369

В статье рассмотрены современные подходы к профилактике вертикальной передачи вирусного гепатита В. Подробно изложены клинические рекомендации по ведению беременности у женщин с хроническим гепатитом В, современные подходы к выбору методов родоразрешения и использованию противовирусных препаратов во время беременности для снижения риска вертикальной передачи. Представлены результаты клинических исследований и метаанализов применения активно-пассивной иммунизации новорожденных. 

The article discusses current approaches for prevention of hepatitis B vertical transmission. Guidelines for management of pregnancy in women with chronic hepatitis B, are presented, as well as modern approaches to the choice of delivery methods and the using of antiviral drugs during pregnancy to reduce the risk of vertical transmission. The results of clinical trials and meta-analyses of neonates active-passive immunization applying are discussed. 

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The authors declare that there are no conflicts of interest present.