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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2014-6-1-5-12</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-213</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Лекции</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Lectures</subject></subj-group></article-categories><title-group><article-title>Лечение малярии (лекция)</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of malaria (lecture)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>профессор кафедры инфекционных болезней Тихоокеанского государственного медицинского университета, д.м.н., профессор; тел.: +7-914-704-56-20</p></bio><email xlink:type="simple">doctor.popov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет, Владивосток</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific Ocean State Medical University, Vladivostokлений</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>16</day><month>09</month><year>2014</year></pub-date><volume>6</volume><issue>1</issue><fpage>5</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попов А.Ф., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Попов А.Ф.</copyright-holder><copyright-holder xml:lang="en">Popov A.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/213">https://journal.niidi.ru/jofin/article/view/213</self-uri><abstract><p>В статье представлена современная стратегия лечения малярии. В отличие от прежних лет, лечение дополняется новой артемизинин-комбинированной терапией – АКТ, где используются два или более противомалярийных препарата с разнонаправленным механизмом действия на P. falciparum. Рекомендовавшийся ранее хинин отнесен к альтернативным противомалярийным средствам, и его применение рекомендуется только в случае отсутствия или невозможности применения артесуната (или артеметера). В то же время при заражении тропической малярией в первом триместре беременности применяют хинин в сочетании с клиндамицином в течение 7 дней. Во втором и третьем триместре назначаются артесунат с клиндамицином. Рассмотрены особенности патогенетической и симптоматической терапии тяжелой малярии.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the current strategy of malaria treating. Unlike previous years, the new treatment is supplemented with artemisinin-based combination therapy – ACT, where two or more anti-malarial drug have multidirectional mechanism of action on P. falciparum. Previously recommended quinine related to alternative antimalarial agents and it is recommended only in case of absence or inability of artesunate (or artemether) using. At the same time, tropical malaria infection during the first trimester is treated by quinine in combination with clindamycin for 7 days. In the second and third trimester artesunate with clindamycin are usually appointed. Pathogenetic and symptomatic features of treatment of severe malaria are observed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>малярия</kwd><kwd>лечение</kwd><kwd>артемизинин</kwd><kwd>комбинированная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>malaria</kwd><kwd>treatment</kwd><kwd>artemisinin</kwd><kwd>combination therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kondrashin AV. Meditsinskaya parazitologiya i parazitarnyye bolezni. 2012; 3: 61-3.</mixed-citation><mixed-citation xml:lang="en">Kondrashin AV. Meditsinskaya parazitologiya i parazitarnyye bolezni. 2012; 3: 61-3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Luchshev VI, Bronshteyn AM. Rossiyskiy meditsinskiy zhurnal. 2010; 2:41-6.</mixed-citation><mixed-citation xml:lang="en">Luchshev VI, Bronshteyn AM. 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