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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2026-18-1-18-25</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-1941</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Роль подвидов Mycobacterium avium в развитии микобактериоза (литературный обзор)</article-title><trans-title-group xml:lang="en"><trans-title>The role of Mycobacterium avium subspecies in the development of mycobacteriosis. Literary review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казюлина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazulina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казюлина Анастасия Александровна – и.о. заведующего научной лабораторией молекулярной биотехнологии НМИЦФИЗ.</p><p>Москва; тел.: +7-963-691-97-28</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">nastellka@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панова</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Panova</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панова Анна Евгеньевна – врио заместителя директора по научной работе Федерального научно-исследовательского института вирусных инфекций «Виром».</p><p>Екатеринбург; тел.: +7-910-418-83-74</p></bio><bio xml:lang="en"><p>Yekaterinburg</p></bio><email xlink:type="simple">anna_panova@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байракова</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Bajrakova</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Байракова Александра Львовна – научный сотрудник НМИЦФИЗ, к.б.н..</p><p>Москва; тел.: +7-977-251-83-54</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">alexandrabl@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байбеков</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bajbekov</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Байбеков Кирилл Сергеевич – младший научный сотрудник научной лаборатории молекулярной биотехнологии НМИЦФИЗ.</p><p>Москва; тел.: 8(495)631-15-15</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">baybecovks@nmrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меренкова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Merenkova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Меренкова Алена Игоревна – младший научный сотрудник научной лаборатории молекулярной биотехнологии НМИЦФИЗ.</p><p>Москва; тел.: 8(495)631-15-15</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">merenkovaai@nmrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюлькова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tjulkova</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тюлькова Татьяна Евгеньевна – главный научный сотрудник научной лаборатории иммунопатологии и иммунодиагностики туберкулезной инфекции НМИЦФИЗ, д.м.н.</p><p>Москва; тел.: 8(495)631-15-15 (1010)</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">tulkova2006@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Phthisiopulmonology and Infectious Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный научно-исследовательский институт вирусных инфекций «Виром»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Institute of Viral Infections «Virom»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2026</year></pub-date><volume>18</volume><issue>1</issue><fpage>18</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Казюлина А.А., Панова А.Е., Байракова А.Л., Байбеков К.С., Меренкова А.И., Тюлькова Т.Е., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Казюлина А.А., Панова А.Е., Байракова А.Л., Байбеков К.С., Меренкова А.И., Тюлькова Т.Е.</copyright-holder><copyright-holder xml:lang="en">Kazulina A.A., Panova A.E., Bajrakova A.L., Bajbekov K.S., Merenkova A.I., Tjulkova T.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/1941">https://journal.niidi.ru/jofin/article/view/1941</self-uri><abstract><p>Микобактерии представляют собой неоднородную группу кислотоустойчивых микроорганизмов, которые могут вызывать различные заболевания человека. Микобактерии, входящие в Mycobacterium avium complex, чаще других регистрируются у больных микобактериозами. К факторам риска, определяющим возможность инфицирования, относят обструктивные хронические заболевания лёгких: бронхиальную астму, бронхоэктазы, туберкулёз и наличие остаточных изменений после его излечения; работу в условиях вредного производства, способствующую развитию заболеваний лёгочной системы. Mycobacterium avium включает 4 подвида: Mycobacterium avium subspecies avium, Mycobacterium avium subspecies silvaticum, Mycobacterium avium subspecies paratuberculosis и Mycobacterium avium subspecies hominissuis. Подвиды Mycobacterium avium отличаются фенотипически и обладают различной патогенностью и влиянием на течение микобактериоза.</p></abstract><trans-abstract xml:lang="en"><p>Микобактерии представляют собой неоднородную группу кислотоустойчивых микроорганизмов, которые могут вызывать различные заболевания человека. Микобактерии, входящие в Mycobacterium avium complex, чаще других регистрируются у больных микобактериозами. К факторам риска, определяющим возможность инфицирования, относят обструктивные хронические заболевания лёгких: бронхиальную астму, бронхоэктазы, туберкулёз и наличие остаточных изменений после его излечения; работу в условиях вредного производства, способствующую развитию заболеваний лёгочной системы. Mycobacterium avium включает 4 подвида: Mycobacterium avium subspecies avium, Mycobacterium avium subspecies silvaticum, Mycobacterium avium subspecies paratuberculosis и Mycobacterium avium subspecies hominissuis. Подвиды Mycobacterium avium отличаются фенотипически и обладают различной патогенностью и влиянием на течение микобактериоза.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нетуберкулезные микобактерии</kwd><kwd>видовая идентификация</kwd><kwd>подвидовая идентификация</kwd><kwd>Mycobacterium avium</kwd><kwd>Mycobacterium avium complex</kwd></kwd-group><kwd-group xml:lang="en"><kwd>нетуберкулезные микобактерии</kwd><kwd>видовая идентификация</kwd><kwd>подвидовая идентификация</kwd><kwd>Mycobacterium avium</kwd><kwd>Mycobacterium avium complex</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Leite F.L. Understanding Mycobacterium avium subspecies hominissuis microaggregate mediated pathogenesis / F.L. Leite // Virulence. – 2015. – № 6(7). – P. 675–676.</mixed-citation><mixed-citation xml:lang="en">Leite F.L. Understanding Mycobacterium avium subspecies hominissuis microaggregate mediated pathogenesis [Текст] / F.L. Leite // Virulence. – 2015. – № 6(7). – P. 675676.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Tran Q.T., Han X.Y. Subspecies identification and significance of 257 clinical strains of Mycobacterium avium / Q.T. Tran, X.Y. Han //journal of Clinical Microbiology. – 2014. – № 52(4). – P. 1201–1206.</mixed-citation><mixed-citation xml:lang="en">Tran Q.T., Han X.Y. Subspecies identification and significance of 257 clinical strains of Mycobacterium avium [Теkst] / Q.T. Tran, X.Y. Han //journal of Clinical Microbiology. – 2014. – № 52(4). – P. 1201-1206.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Yano H. Population Structure and Local Adaptation of MAC Lung Disease Agent Mycobacterium avium subsp. hominissuis / H. Yano, T. Iwamoto, Y. Nishiuchi [et al.] // Genome Biology and Evolution. – 2017. – Vol. 9, № 9. – P. 2403–2417.</mixed-citation><mixed-citation xml:lang="en">Yano H. Population Structure and Local Adaptation of MAC Lung Disease Agent Mycobacterium avium subsp. hominissuis [Теkst] / H. Yano, T. Iwamoto, Y. Nishiuchi [и др.] // Genome Biology and Evolution. – 2017. – Vol. 9, № 9. – P. 2403-2417.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнова, Т.Г. Смешанные популяции микобактерий у больных туберкулезом и микобактериозом: частота выявления и спектр видов / Т.Г. Смирнова, С.Н. Андреевская, Е.Е. Ларионова [и др.] // Туберкулез и социально значимые заболевания. – 2023. – № 11 (2). – С. 19–24.</mixed-citation><mixed-citation xml:lang="en">Smirnova, T. G. Smeshannye populyacii mikobakterij u bol’nyh tuberkulezom i mikobakteriozom: chastota vyyavleniya i spektr vidov [Tekst] / T. G. Smirnova, S. N. Andreevskaya, E. E. Larionova [i dr.] // Tuberkulez i social’no znachimye zabolevaniya. – 2023. – № 11(2). – S. 19-24.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин, А.Г. Респираторная медицина : в 3 т. / А.Г. Чучалин. – 2-е изд., перераб. и доп. – М.: Литтерра, 2017. – Т. 1. – 544 с.</mixed-citation><mixed-citation xml:lang="en">Chuchalin, A. G. Respiratornaya medicina [Tekst] : v 3 t. / A. G. Chuchalin. – 2-e izd., pererab. i dop. – Moskva : Litterra, 2017. – T. 1. – 544 s.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Веселова, Е.И. Этиология поражений легких у больных ВИЧ-инфекцией на стадии 4В / Е.И. Веселова, О.А. Преснякова, В.В. Тинькова, Е.Н. Белобородова // Инфекционные болезни в современном мире: эволюция, текущие и будущие угрозы : материалы XVI ежегодного Всероссийского конгресса по инфекционным болезням им. акад. В.И. Покровского. – М.: ООО «ММА», 2024. – С. 47.</mixed-citation><mixed-citation xml:lang="en">Veselova, E.I. Etiologiya porazhenij legkih u bol’nyh VICH-infekciej na stadii 4V [Tekst] / E.I. Veselova, O.A. Presnyakova, V.V. Tin’kova, E. N. Beloborodova // Infekcionnye bolezni v sovremennom mire: evolyuciya, tekushchie i budushchie ugrozy : materialy XVI ezhegodnogo Vserossijskogo kongressa po infekcionnym boleznyam im. akad. V.I. Pokrovskogo. – Moskva : OOO «MMA», 2024. – S. 47.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wynne J.W. Resequencing the Mycobacterium avium subsp. paratuberculosis K10 genome: improved annotation and revised genome sequence /j.W. Wynne, T. Seemann, D.M. Bulach [et al.] //journal of Bacteriology. – 2010. – Vol. 192, № 23. – P. 6319–6320.</mixed-citation><mixed-citation xml:lang="en">Wynne J.W. Resequencing the Mycobacterium avium subsp. paratuberculosis K10 genome: improved annotation and revised genome sequence /j.W. Wynne, T. Seemann, D.M. Bulach [et al.] //journal of Bacteriology. – 2010. – Vol. 192, № 23. – P. 6319–6320.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Parolina L. Clinical characteristics of COVID-19 in patients with tuberculosis and factors associated with the disease severity / L. Parolina, N. Pshenichnaya, I. Vasilyeva [et al.] // International Journal of Infectious Diseases. – 2022. – Vol. 124. – P. 82-89.</mixed-citation><mixed-citation xml:lang="en">Parolina L. Clinical characteristics of COVID-19 in patients with tuberculosis and factors associated with the disease severity [Теkst] / L. Parolina, N. Pshenichnaya, I. Vasilyeva [и др.] // International Journal of Infectious Diseases. – 2022. – Vol. 124. – P. 82-89.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tuberculosis and COVID-19 co-infection: description of the global cohort / TB/COVID-19 Global Study Group // European Respiratory Journal. – 2022. – Vol. 59, № 3. – P. 2102538.</mixed-citation><mixed-citation xml:lang="en">Tuberculosis and COVID-19 co-infection: description of the global cohort [Теkst] / TB/COVID-19 Global Study Group // European Respiratory Journal. – 2022. – Vol. 59, № 3. – P. 2102538.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Zarei-Kordshouli F. Prevalence of Mycobacterium avium subspecies paratuberculosis IS 900 DNA in biopsy tissues from patients with Crohn’s disease: histopathological and molecular comparison with Johne’s disease in Fars province of Iran / F. Zarei-Kordshouli, B. Geramizadeh, A. Khodakaram-Tafti // BMC Infectious Diseases. – 2019. – Vol. 19, № 1. – P. 23.</mixed-citation><mixed-citation xml:lang="en">Zarei-Kordshouli F. Prevalence of Mycobacterium avium subspecies paratuberculosis IS 900 DNA in biopsy tissues from patients with Crohn’s disease: histopathological and molecular comparison with Johne’s disease in Fars province of Iran [Теkst] / F. Zarei-Kordshouli, B. Geramizadeh, A. KhodakaramTafti // BMC Infectious Diseases. – 2019. – Vol. 19, №1. – P. 23.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Chester F.D. A Manual of Determinative Bacteriology / F.D. Chester // Science. – 1901. – Vol. 14, № 364. – P. 967– 969.</mixed-citation><mixed-citation xml:lang="en">Chester F.D. A Manual of Determinative Bacteriology [Теkst] / F.D. Chester // Science. – 1901. – Vol. 14, № 364. – P. 967-969.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta R.S. Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera / R.S. Gupta, B. Lo, J. Son // Frontiers in Microbiology. – 2018. – Vol. 9. – P. 67.</mixed-citation><mixed-citation xml:lang="en">Gupta R.S. Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera [Теkst] / R.S. Gupta, B. Lo, J. Son // Frontiers in Microbiology. – 2018. – Vol. 9. – P. 67.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Akram S.M. Mycobacterium avium Complex / S.M. Akram, F.N. Attia. – Treasure Island (FL) : StatPearls Publishing, 2024. – 1 р.</mixed-citation><mixed-citation xml:lang="en">Akram S.M. Mycobacterium avium Complex [Теkst] / S.M. Akram, F.N. Attia. – Treasure Island (FL) : StatPearls Publishing, 2024. – 1 р.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Busatto C. Mycobacterium avium: an overview / C. Busatto, J.S. Vianna, L.V. da Silva [et al.] // Tuberculosis. – 2019. – Vol. 114. – P. 127–134.</mixed-citation><mixed-citation xml:lang="en">Busatto C. Mycobacterium avium: an overview [Теkst] / C. Busatto, J.S. Vianna, L.V. da Silva [и др.] // Tuberculosis. – 2019. – Vol. 114. – P. 127-134.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Rindi L. Genetic diversity and phylogeny of Mycobacterium avium / L. Rindi, C. Garzelli // Infection, Genetics and Evolution. – 2014. – Vol. 21. – P. 375–383.</mixed-citation><mixed-citation xml:lang="en">Rindi L. Genetic diversity and phylogeny of Mycobacterium avium [Теkst] / L. Rindi, C. Garzelli // Infection, Genetics and Evolution. – 2014. – Vol. 21. – P. 375-383.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Зимина, В.Н. Микобактериозы: современное состояние проблемы / В. Н. Зимина, С. Ю. Дегтярева, Е. Н. Белобородова [и др.] // КМАХ. – 2017. – Т. 19, № 4. – С. 276–282.</mixed-citation><mixed-citation xml:lang="en">Zimina, V. N. Mikobakteriozy: sovremennoe sostoyanie problemy [Tekst] / V. N. Zimina, S. YU. Degtyareva, E. N. Beloborodova [i dr.] // KMAH. – 2017. – T. 19, № 4. – S. 276-282.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wetzstein N. Clinical and genomic features of Mycobacterium avium complex: a multi-national European study / N. Wetzstein, M. Diricks, T.B. Anton [et al.] // Genome Medicine. – 2024. – Vol. 16, № 86. – P. 1-12.</mixed-citation><mixed-citation xml:lang="en">Wetzstein N. Clinical and genomic features of Mycobacterium avium complex: a multi-national European study [Теkst] / N. Wetzstein, M. Diricks, T.B. Anton [и др.] // Genome Medicine. – 2024. – Vol. 16, № 86. – P. 1-12.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Лямин, А.В. Нетуберкулезные микобактерии: современные возможности видовой идентификации / А.В. Лямин, А.М. Ковалёв, А.В. Жестков [и др.] // КМАХ. – 2017. – Т. 19, № 1 – С. 11–14.</mixed-citation><mixed-citation xml:lang="en">Lyamin, A. V. Netuberkuleznye mikobakterii: sovremennye vozmozhnosti vidovoj identifikacii [Tekst] / A. V. Lyamin, A. M. Kovalyov, A. V. ZHestkov [i dr.] // KMAH. — 2017. — T. 19, № 1 — S. 11-14.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Griffith, D. E. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases / D. E. Griffith, T. Aksamit, B. A. Brown-Elliott [et al.] // American Journal of Respiratory and Critical Care Medicine. – 2007. – Vol. 175, № 4. – P. 367–416.</mixed-citation><mixed-citation xml:lang="en">Griffith, D. E. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases [Теkst] / D. E. Griffith, T. Aksamit, B. A. Brown-Elliott [и др.] // American Journal of Respiratory and Critical Care Medicine. – 2007. – Vol. 175, № 4. – P. 367–416.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Floto, R.A. US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis / Floto R.A., Olivier K.N., Saiman L., Daley C.L. [et al.] // Thorax. – 2016. – Vol. 71, № 1. – P. 11–22.</mixed-citation><mixed-citation xml:lang="en">Floto, R.A. US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis [Теkst] / Floto R.A., Olivier K.N., Saiman L., Daley C.L. [и др.] // Thorax. – 2016. – Vol. 71, № 1. – P. i122.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lange, C. Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases / C. Lange, E.C. Böttger, E. Cambau [et al.] // The Lancet Infectious Diseases. – 2022. – Vol. 22, № 7. – P. e178–e190.</mixed-citation><mixed-citation xml:lang="en">Lange, C. Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases [Теkst] / C. Lange, E. C. Böttger, E. Cambau [и др.] // The Lancet Infectious Diseases. – 2022. – Vol. 22, № 7. – P. e178–e190.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Daley, C.L. Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline / C.L. Daley, J.M. Iaccarino, C. Lange [at al.] // European Respiratory Journal. – 2020. – Vol. 56, № 1. – P. e1– e36.</mixed-citation><mixed-citation xml:lang="en">Daley, C. L. Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline [Теkst] / C. L. Daley, J. M. Iaccarino, C. Lange [и др.] // European Respiratory Journal. – 2020. – Vol. 56, № 1. – P. e1e36.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Kaplan, J. E. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America /j.E. Kaplan, C. Benson, K.K. Holmes [et al.] // MMWR Recommendations and Reports. – 2009. – Vol. 58, № RR-4. – P. 1–207.</mixed-citation><mixed-citation xml:lang="en">Kaplan, J. E. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America [Теkst] /j. E. Kaplan, C. Benson, K. K. Holmes [и др.] // MMWR Recommendations and Reports. – 2009. – Vol. 58, № RR-4. – P. 1–207.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Tryland M. Serologic survey for antibodies against Mycobacterium avium subsp. paratuberculosis in free-ranging cervids from Norway / M. Tryland, I. Olsen, T. Vikøren [et al.] //journal of Wildlife Diseases. – 2004. – Vol. 40, № 1. – P. 32–41.</mixed-citation><mixed-citation xml:lang="en">Tryland M. Serologic survey for antibodies against Mycobacterium avium subsp. paratuberculosis in free-ranging cervids from Norway [Теkst] / M. Tryland, I. Olsen, T. Vikøren [и др.] //journal of Wildlife Diseases. – 2004. – Vol. 40, № 1. – P. 32-41.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Agrawal G. ‘Global warming’ to Mycobacterium avium subspecies paratuberculosis / G. Agrawal, T.J. Borody, W. Chamberlin // Future Microbiology. – 2014. – Vol. 9, №7. – P. 829–832.</mixed-citation><mixed-citation xml:lang="en">Agrawal G. ‘Global warming’ to Mycobacterium avium subspecies paratuberculosis [Теkst] / G. Agrawal, T.J. Borody, W. Chamberlin // Future Microbiology. – 2014. – Vol. 9, № 7. – P. 829-832.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kalvisa A. MIRU-VNTR genotype diversity and indications of homoplasy in M. avium strains isolated from humans and slaughter pigs in Latvia / A. Kalvisa, C. Tsirogiannis, I. Silamikelis [et al.] // Infection, Genetics and Evolution. – 2016. – Vol. 43. – P. 15–21.</mixed-citation><mixed-citation xml:lang="en">Kalvisa A. MIRU-VNTR genotype diversity and indications of homoplasy in M. avium strains isolated from humans and slaughter pigs in Latvia [Теkst] / A. Kalvisa, C. Tsirogiannis, I. Silamikelis [и др.] // Infection, Genetics and Evolution. – 2016. – Vol. 43. – P. 15-21.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Agdestein A. A comparative study of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis in experimentally infected pigs / A. Agdestein, T.B. Johansen, Ø. Kolbjørnsen [et al.] // BMC Veterinary Research. – 2012. – Vol. 8. – P. 11.</mixed-citation><mixed-citation xml:lang="en">Agdestein A. A comparative study of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis in experimentally infected pigs [Теkst] / A. Agdestein, T.B. Johansen, Ø. Kolbjørnsen [и др.] // BMC Veterinary Research. – 2012. – Vol. 8. – P. 11.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tirkkonen T. High genetic relatedness among Mycobacterium avium strains isolated from pigs and humans revealed by comparative IS1245 RFLP analysis / T. Tirkkonen, J. Pakarinen, A.M. Moisander [et al.] // Veterinary Microbiology. – 2007. – Vol. 125, № 1–2. – P. 175–181.</mixed-citation><mixed-citation xml:lang="en">Tirkkonen T. High genetic relatedness among Mycobacterium avium strains isolated from pigs and humans revealed by comparative IS1245 RFLP analysis [Теkst] / T. Tirkkonen, J. Pakarinen, A.M. Moisander [и др.] // Veterinary Microbiology. – 2007. – Vol. 125, № 1-2. – P. 175-181.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Старкова, Д.А. Полиморфизм однонуклеотидных замен в генах hsp65 и MACPPE12 Mycobacterium avium subsp. hominissus / Д.А. Старкова, T. Iwamoto, А.А. Вязова [и др.] // Генетика. – 2019. – Т. 55, № 5. – С. 516–524.</mixed-citation><mixed-citation xml:lang="en">Starkova, D. A. Polimorfizm odnonukleotidnyh zamen v genah hsp65 i MACPPE12 Mycobacterium avium subsp. hominissus [Tekst] / D. A. Starkova, T. Iwamoto, A. A. Vyazova [i dr.] // Genetika. – 2019. – T. 55, № 5. – S. 516-524.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bruijnesteijn van Coppenraet L.E. Lymphadenitis in children is caused by Mycobacterium avium hominissuis and not related to ‘bird tuberculosis’ / L.E. Bruijnesteijn van Coppenraet, P.E. de Haas, J.A. Lindeboom [et al.] // European Journal of Clinical Microbiology &amp; Infectious Diseases. – 2008. – Vol. 27, № 4. – P. 293–299.</mixed-citation><mixed-citation xml:lang="en">Bruijnesteijn van Coppenraet L.E. Lymphadenitis in children is caused by Mycobacterium avium hominissuis and not related to ‘bird tuberculosis’ [Теkst] / L.E. Bruijnesteijn van Coppenraet, P.E. de Haas, J.A. Lindeboom [и др.] // European Journal of Clinical Microbiology &amp; Infectious Diseases. – 2008. – Vol. 27, № 4. – P. 293-299.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Turenne C.Y. Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organisms / C.Y. Turenne, D.M. Collins, D.C. Alexander, M.A. Behr //journal of Bacteriology. – 2008. – Vol. 190, № 7. – P. 2479–2487.</mixed-citation><mixed-citation xml:lang="en">Turenne C.Y. Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organisms [Теkst] / C.Y. Turenne, D.M. Collins, D.C. Alexander, M.A. Behr //journal of Bacteriology. – 2008. – Vol. 190, №7. – P. 2479-2487.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Timms V.J. The Association of Mycobacterium avium subsp. paratuberculosis with Inflammatory Bowel Disease / V.J. Timms, G. Daskalopoulos, H.M. Mitchell, B.A. Neilan // PLoS ONE. – 2016. – Vol. 11, № 2. – P. e0148731.</mixed-citation><mixed-citation xml:lang="en">Timms V.J. The Association of Mycobacterium avium subsp. paratuberculosis with Inflammatory Bowel Disease [Теkst] / V.J. Timms, G. Daskalopoulos, H.M. Mitchell, B.A. Neilan // PLoS ONE. – 2016. – Vol. 11, № 2. – P. e0148731.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Feller M. Mycobacterium avium subspecies paratuberculosis and Crohn’s disease: a systematic review and meta-analysis / M. Feller, K. Huwiler, R. Stephan [et al.] // The Lancet. Infectious Diseases. – 2007. – Vol. 7, № 9. – P. 607–613.</mixed-citation><mixed-citation xml:lang="en">Feller M. Mycobacterium avium subspecies paratuberculosis and Crohn’s disease: a systematic review and meta-analysis [Теkst] / M. Feller, K. Huwiler, R. Stephan [и др.] // The Lancet. Infectious Diseases. – 2007. – Vol. 7, № 9. – P. 607-613.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Schwartz D. Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn’s disease patients / D. Schwartz, I. Shafran, C. Romero [et al.] // Clinical Microbiology and Infection. – 2000. – Vol. 6, № 6. – P. 303–307.</mixed-citation><mixed-citation xml:lang="en">Schwartz D. Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn’s disease patients [Теkst] / D. Schwartz, I. Shafran, C. Romero [и др.] // Clinical Microbiology and Infection. – 2000. – Vol. 6, № 6. – P. 303-307.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Mintz M.J. Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn’s disease: the debate continues / M.J. Mintz, D.J. Lukin // Translational Gastroenterology and Hepatology. – 2023. – Vol. 8. – P. 28.</mixed-citation><mixed-citation xml:lang="en">Mintz M.J. Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn’s disease: the debate continues [Теkst] / M.J. Mintz, D.J. Lukin // Translational Gastroenterology and Hepatology. – 2023. – Vol. 8. – P. 28.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Moghadam M. Mycobacterium avium subsp. paratuberculosis and Hashimoto’s thyroiditis: Is MAP the trigger? / M. Moghadam, E.A. Ghaemi, H. Akbari [et al.] // Frontiers in Cellular and Infection Microbiology. – 2022. – Vol. 12. – P. 972929.</mixed-citation><mixed-citation xml:lang="en">Moghadam M. Mycobacterium avium subsp. paratuberculosis and Hashimoto’s thyroiditis: Is MAP the trigger? [Теkst] / M. Moghadam, E.A. Ghaemi, H. Akbari [et al.] // Frontiers in Cellular and Infection Microbiology. – 2022. – Vol. 12. – P. 972929.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Alvarez J. Genetic diversity of Mycobacterium avium isolates recovered from clinical samples and from the environment: molecular characterization for diagnostic purposes /j. Alvarez, I.G. García, A. Aranaz [et al.] //journal of Clinical Microbiology. – 2008. – Vol. 46, № 4. – P. 1246–1251.</mixed-citation><mixed-citation xml:lang="en">Alvarez J. Genetic diversity of Mycobacterium avium isolates recovered from clinical samples and from the environment: molecular characterization for diagnostic purposes [Теkst] /j. Alvarez, I.G. García, A. Aranaz [et al.] //journal of Clinical Microbiology. – 2008. – Vol. 46, № 4. – P. 1246-1251.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Singh S.V. Concurrent Resolution of Chronic Diarrhea Likely Due to Crohn’s Disease and Infection with Mycobacterium avium paratuberculosis / S.V. Singh, J.T. Kuenstner, W.C. Davis [et al.] // Frontiers in Medicine. – 2016. – Vol. 3. – P. 49.</mixed-citation><mixed-citation xml:lang="en">Singh S.V. Concurrent Resolution of Chronic Diarrhea Likely Due to Crohn’s Disease and Infection with Mycobacterium avium paratuberculosis [Теkst] / S.V. Singh, J.T. Kuenstner, W.C. Davis [и др.] // Frontiers in Medicine. – 2016. – Vol. 3. – P. 49.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Старкова, Д.А. Генотипическая характеристика штаммов Mycobacterium avium subsp. hominissus / Д.А. Старкова, И.В. Мокроусов, А.А. Вязовая [и др.] // Генетика. – 2013. – Т. 49, № 4. – С. 14–19.</mixed-citation><mixed-citation xml:lang="en">Starkova, D. A. Genotipicheskaya harakteristika shtammov Mycobacterium avium subsp. hominissus [Tekst] / D.A. Starkova, I. V. Mokrousov, A. A. Vyazovaya [i dr.] // Genetika. – 2013. – T. 49, № 4. – S. 14-19.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Vluggen C. Genotyping and strain distribution of Mycobacterium avium subspecies hominissuis isolated from humans and pigs in Belgium, 2011-2013 / C. Vluggen, K. Soetaert, L. Duytschaever [et al.] // Eurosurveillance. – 2016. – Vol. 21, № 3. – P. 30111.</mixed-citation><mixed-citation xml:lang="en">Vluggen C. Genotyping and strain distribution of Mycobacterium avium subspecies hominissuis isolated from humans and pigs in Belgium, 2011-2013 [Теkst] / C. Vluggen, K. Soetaert, L. Duytschaever [et al.] // Eurosurveillance. – 2016. – Vol. 21, № 3. – P. 30111.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Chang C.L. Different clinical features of patients with pulmonary disease caused by various Mycobacterium aviumintracellulare complex subspecies and antimicrobial susceptibility / C.L. Chang, L.C. Chen, C.J. Yu, P.R. Hsueh, J.Y. Chien // International Journal of Infectious Diseases. – 2020. – Vol. 98. – P. 33–40.</mixed-citation><mixed-citation xml:lang="en">Chang C.L. Different clinical features of patients with pulmonary disease caused by various Mycobacterium aviumintracellulare complex subspecies and antimicrobial susceptibility [Теkst] / C.L. Chang, L.C. Chen, C.J. Yu, P.R. Hsueh, J.Y. Chien // International Journal of Infectious Diseases. – 2020. – Vol. 98. – P. 33-40.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Agdestein A. Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection / A. Agdestein, A. Jones, A. Flatberg [et al.] // BMC Genomics. – 2014. – Vol. 15. – P. 58.</mixed-citation><mixed-citation xml:lang="en">Agdestein A. Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection [Теkst] / A. Agdestein, A. Jones, A. Flatberg [et al.] // BMC Genomics. – 2014. – Vol. 15. – P. 58.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Algammal A.M. Emerging MDR-Mycobacterium avium subsp. avium in house-reared domestic birds as the first report in Egypt / A.M. Algammal, H.R. Hashem, A.S. Al-Otaibi [et al.] // BMC Microbiology. – 2021. – Vol. 21. – P. 237.</mixed-citation><mixed-citation xml:lang="en">Algammal A.M. Emerging MDR-Mycobacterium avium subsp. avium in house-reared domestic birds as the first report in Egypt [Теkst] / A.M. Algammal, H.R. Hashem, A.S. Al-Otaibi [et al.] // BMC Microbiology. – 2021. – Vol. 21. – P. 237.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
