jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2025-17-2-21-31jofin-1779Research ArticleОбзорыReviewСовременные данные о биологии вируса герпеса человека 6 типа и патогенезе ассоциированных с ним клинических состояний (обзор научных публикаций)Modern data on the biology of Human Herpesvirus 6 and pathogenesis of Human Herpesvirus 6-associated clinical conditions (review of scientific publications)ДроздовскаяП. А.DrozdovskayaP. A.

Дроздовская Полина Андреевна – лаборант-исследователь отдела патоморфологии ЦДТИ ИЭМ; студентка 

Санкт-Петербург

Saint-Petersburg

drozdovskaya.p@mail.ruЦинзерлингВ. А.ZinserlingV. A.

Цинзерлинг Всеволод Александрович – заведующий отделом патоморфологии ЦДТИ ИЭМ; профессор кафедры; руководитель центра инфекционнойпатологии, д.м.н., профессор

Санкт-Петербург

Saint-Petersburg

zinserling@yandex.ruНациональный медицинский исследовательский центр им В.А. Алмазова; Северо-Западный государственный медицинский университета им. И.И. МечниковаРоссияNational Medical Research Centre named after V.A. Almazov; North-Western State Medical University named after I.I. MechnikovRussian FederationНациональный медицинский исследовательский центр им В.А. Алмазова; Северо-Западный государственный медицинский университета им. И.И. Мечникова; Клиническая инфекционная больница им. С.П. БоткинаРоссияNational Medical Research Centre named after V.A. Almazov; North-Western State Medical University named after I.I. Mechnikov; Clinical Infectious Diseases Hospital named after S.P. BotkinRussian Federation2025240620251722131Copyright © Дроздовская П.А., Цинзерлинг В.А., 20252025Дроздовская П.А., Цинзерлинг В.А.Drozdovskaya P.A., Zinserling V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/1779

Несмотря на практически всеобщую инфицированность населения вирусом герпеса человека 6 типа во всем мире (до 90% людей считаются серопозитивными), герпес-ассоциированные заболевания остаются малоизученными. За последние 10 лет представления об этом микроорганизме значительно уточнились. В обзоре представлены современные данные о биологических свойствах вируса герпеса человека 6 типа, освещены эпидемиология, разнообразие клинических форм и вариантов течения инфекции, патогенез заболевания. Описаны специфические патогенетические особенности вируса герпеса человека 6 типа, определяющие трудности лабораторной диагностики инфекции и постановки диагноза и создающие проблемы при выборе тактики лечения.

Despite almost universal detection of human herpesvirus 6 in general population (up to 90% of individuals are considered seropositive), human herpesvirus 6-associated diseases remain poorly explored. Knowledge of this microorganism has greatly increased over the recent 10 years. The review presents modern data on the biological properties of the human herpesvirus 6, highlights the epidemiology, variety of clinical forms and variants of the course of the disease, pathogenesis of the infection. Specific features of the human herpesvirus 6 were described. They determine difficulties of laboratory diagnostics of the infection and create problems in choosing treatment tactics.

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The authors declare that there are no conflicts of interest present.