jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2024-16-2-75-80jofin-1642Research ArticleОригинальное исследованиеOriginal ResearchКлинико-лабораторная характеристика COVID-19 в динамике болезни у взрослых: щитовидная железа и надпочечникиClinical and laboratory characteristics of COVID-19 in the dynamics of the disease in adults: thyroid and adrenal glandsМаликоваЯ. В.MalikovaYa. V.

Маликова Яна Владимировна – аспирант кафедры инфекционных болезней

Уфа

Ufa

doctor_malikova@mail.ruВалишинД. А.ValishinD. A.

Валишин Дамир Асхатович – заведующий кафедрой инфекционных болезней; д.м.н.; профессор

Уфа

Ufa

damirval@yandex.ruМурзабаеваР. Т.MurzabaevaR. T.

Мурзабаева Расима Тимеряровна – доктор медицинских наук; профессор кафедры инфекционных болезней; д.м.н.

Уфа

Ufa

rmurzabaeva@yandex.ruЯппаровР. Г.YapparovR. G.

Яппаров Рафаэль Галиевич – главный врач; к.м.н.

Уфа

Ufa

rafdok@yandex.ruБашкирский государственный медицинский университетРоссияBashkir State Medical UniversityRussian FederationРеспубликанский центр по профилактике и борьбе со СПИДом и инфекционными заболеваниямиРоссияRepublican Center for the Prevention and Control of AIDS and Infectious DiseasesRussian Federation2024100720241627580Copyright © Маликова Я.В., Валишин Д.А., Мурзабаева Р.Т., Яппаров Р.Г., 20242024Маликова Я.В., Валишин Д.А., Мурзабаева Р.Т., Яппаров Р.Г.Malikova Y.V., Valishin D.A., Murzabaeva R.T., Yapparov R.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/1642Цель

Цель: оценить влияние COVID-19 на развитие эндокринной патологии у исследуемых взрослых пациентов

Материалы и методы

Материалы и методы: проведены клиниколабораторные исследования у 166 пациентов в возрасте 18–65 лет с подтвержденным диагнозом коронавирусной инфекции U07.1 (COVID-19); со среднетяжелым (140 пациентов) и тяжелым (26 пациентов) течением болезни. В контрольную группу вошли 35 практически здоровых лиц в возрасте от 18 до 65 лет.

Результаты

Результаты: в острый период COVID-19 выявлено развитие субклинического гипотиреоза; синдрома низкого Т3; субклинического тиреотоксикоза; а также гипои гиперкортизолемии. Через 6 месяцев после выписки из стационара в амбулаторных условиях у реконвалесцентов COVID-19 было выявлено развитие патологии щитовидной железы у 6 и сахарного диабета у 5 пациентов. 

Objective

Objective: to evaluate the effect of COVID-19 on the development of endocrine pathology in the studied adult patients

Materials and methods

Materials and methods: Clinical and laboratory studies were conducted in 166 patients aged 18-65 years with a confirmed diagnosis of coronavirus infection U07.1 (COVID-19); with moderate (140 patients) and severe (26 patients) course of the disease. The control group included 35 practically healthy individuals aged 18 to 65 years.

Results

Results: In the acute period of COVID-19; the development of subclinical hypothyroidism; low T3 syndrome; subclinical thyrotoxicosis; as well as hypoand hypercortisolemia was revealed. 6 months after discharge from the hospital on an outpatient basis; the development of thyroid pathology in 6 patients and diabetes mellitus in 5 patients was revealed in COVID-19 convalescents.

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The authors declare that there are no conflicts of interest present.