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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2021-13-1-29-37</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-1175</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Международный опыт вакцинации беременных против коклюша (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>International practice in vaccination of pregnant women against pertussis (a review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харит</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharit</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Харит Сусанна Михайловна – руководитель отдела профилактики инфекционных болезней Детского научно-клинического центра инфекционных болезней, д.м.н., профессор</p><p>Санкт-Петербургтел.: 8(812)234-68-55</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">kharit-s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>Ю. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinova</surname><given-names>Yu. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Константинова Юлия Евгеньевна – младший научный сотрудник отдела профилактики инфекционных болезней</p><p>Санкт-Петербургтел.: 8(812)234-68-55</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">yulia.konstantinova23@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Детский научно-клинический центр инфекционных болезней; Санкт-Петербургский государственный педиатрический медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pediatric Research and Clinical Center for Infectious Disease; Saint-Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Детский научно-клинический центр инфекционных болезней</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pediatric Research and Clinical Center for Infectious Disease</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2021</year></pub-date><volume>13</volume><issue>1</issue><fpage>29</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Харит С.М., Константинова Ю.Е., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Харит С.М., Константинова Ю.Е.</copyright-holder><copyright-holder xml:lang="en">Kharit S.M., Konstantinova Y.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/1175">https://journal.niidi.ru/jofin/article/view/1175</self-uri><abstract><p>Коклюш в России по-прежнему остается актуальной проблемой здравоохранения, несмотря на проводимую в течение многих десятилетий вакцинацию. Группой высокого риска тяжелого течения коклюша и смерти от него являются дети до 1 года, не получившие плановой вакцинации или не привитые по возрасту (первых месяцев жизни). Всемирная организация здравоохранения признает наиболее эффективным методом профилактики коклюша у детей до того, как они получат три плановые прививки, вакцинацию беременных. Мировой опыт по программам иммунизации беременных женщин против коклюша показывает, что до 91% детей до 3 месяцев жизни защищены от коклюша в результате трансплацентарной передачи антител, сформированных у матери после ее вакцинации (что соотносится со сроками вакцинации детей против коклюша в России: первая прививка в возрасте 3 месяцев). Максимальный профилактический эффект для ребенка отмечен при иммунизации беременной женщины на 28–32-й неделе гестации. Показана безопасность вакцинации, как для матери, так и для ребенка. Серьезные нежелательные явления, связанные с вакцинацией, зарегистрированы не были. Охват беременных вакцинацией в разных странах достигает 51–70%. С целью повышения приверженности к вакцинации беременных следует регулярно обучать медицинский персонал основам вакцинопрофилактики, а также проводить активную санитарно-просветительскую работу среди населения.</p></abstract><trans-abstract xml:lang="en"><p>Whooping cough is still an urgent health problem in Russia, despite the vaccination that has been carried out for many decades. The group at high risk of severe whooping cough and death from it is children under 1 year old who have not received routine vaccination or are not vaccinated by age (the first months of life). The world health organization recognizes vaccination of pregnant women as the most effective method of preventing whooping cough in children before they receive three routine vaccinations. World experience in immunization programs for pregnant women against pertussis shows that up to 91% of children under 3 months of life are protected from pertussis as a result of transplacental transmission of antibodies formed in the mother after her vaccination (which corresponds to the timing of vaccination of children against pertussis in Russia: the first vaccination at the age of 3 months). The maximum preventive effect for a child was observed when a pregnant woman was immunized at 28–32 weeks of gestation. The safety of vaccination for both mother and child is shown. No serious adverse events related to vaccination have been reported. Coverage of pregnant women with vaccination in different countries reaches 51-70%. In order to increase adherence to vaccination of pregnant women, medical personnel should be regularly trained in the basics of vaccination, as well as conduct active health education among the population.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вакцинация беременных</kwd><kwd>коклюш</kwd><kwd>дети</kwd><kwd>новорожденные</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vaccination</kwd><kwd>pregnant women</kwd><kwd>pertussis</kwd><kwd>whooping cough</kwd><kwd>infants</kwd><kwd>newborn</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pertussis vaccines: WHO position paper [Internet]. Weekly epidemiological record; 2015 Aug [cited 31.08.2020]. Available from: https://www.who.int/wer/2015/wer9035.pdf?ua=1</mixed-citation><mixed-citation xml:lang="en">Pertussis vaccines: WHO position paper [Internet]. 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