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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2020-12-4-19-22</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-1097</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Особенности клинического течения риновирусной инфекции у госпитализированных взрослых больных в эпидемический сезон 2017–2018 гг.</article-title><trans-title-group xml:lang="en"><trans-title>Clinical features of rhinovirus infection in hospitalized adult patients during the epidemic season 2017–2018</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бичурина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bichurina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующая лабораторией этиологии и контроля вирусных инфекций, д.м.н.,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">romanenkova@pasteurorg.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волощук</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Voloshchuk</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории этиологии и контроля вирусных инфекций, к.м.н.,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">romanenkova@pasteurorg.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Го</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Go</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-инфекционист клиники, к.м.н.,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">alexeigo@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Писарева</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pisareva</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории молекулярной вирусологии, к.м.н.,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">maria.pisareva@influenza.spb.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гужов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Guzhov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отделения ОРВИ у взрослых,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">dimas1992@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg Research Institute of Epidemiology and Microbiology named after Pasteur</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт гриппа им. А.А. Смородинцева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg Research Institute of Epidemiology and Microbiology named after Pasteur</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт гриппа им. А.А. Смородинцева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research institute of influenza named after A.A. Smorodintsev</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2020</year></pub-date><volume>12</volume><issue>4</issue><fpage>19</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бичурина М.А., Волощук Л.В., Го А., Писарева М.М., Гужов Д.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бичурина М.А., Волощук Л.В., Го А., Писарева М.М., Гужов Д.А.</copyright-holder><copyright-holder xml:lang="en">Bichurina M.A., Voloshchuk L.V., Go A., Pisareva M.M., Guzhov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/1097">https://journal.niidi.ru/jofin/article/view/1097</self-uri><abstract><sec><title>Цель</title><p>Цель. Риновирусная (РВ) инфекция в прошлом воспринималась как заболевание, способное вызывать легкие респираторные симптомы в большинстве случаев у детей. Современные клинико-эпидемиологические исследования показали, что РВ-инфекция у взрослых и детей имеет среднетяжелое и тяжелое течение. Целью настоящего исследования было проведение клинико-лабораторного анализа случаев риновирусной инфекции у взрослых госпитализированных больных и оценка этиологического значения риновирусов в эпидемический сезон 2017–2018 гг.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Изучено 1013 историй болезни пациентов, обследованных методом ПЦР, из них 51 с РВ инфекцией.</p></sec><sec><title>Результаты</title><p>Результаты. Из обследованных больных у 41,6% выявлен грипп, у 45,8% вирусы не обнаружены и у 12,6% выявлены другие вирусные инфекции, из которых 40% приходится на РВ. Среди них преобладали пациенты молодого возраста: медиана для мужчин – 31,0 лет, для женщин – 27,5 лет. Заболевание протекало в среднетяжелой форме – 78,8%, тяжелое течение было отмечено у 5,3% больных и сопровождалось инфекционно-токсическим шоком. Заболевание наиболее часто осложнялось острым бронхитом – 22,1%, в 15,7% случаев присоединялась пневмония.</p></sec><sec><title>Заключение</title><p>Заключение. РВ-инфекция занимает первое место (40%) среди негриппозных причин вирусного поражения респираторного тракта у обследованных пациентов. Она регистрировалась преимущественно у лиц молодого возраста. В большинстве случаев протекала в среднетяжелой форме и имела осложненное течение, в том числе пневмонией. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. Rhinovirus infection has in the past been perceived as a disease capable of causing mild respiratory symptoms in most cases in children. Modern clinical and epidemiological studies have shown that rhinovirus infection in adults and children and has a moderate and severe course. The aim of this study was to conduct a clinical and laboratory analysis of cases of rhinovirus infection in adult hospitalized patients and evaluate the etiological role of rinoviruses in the epidemic season of 2017/18.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 1013 case histories of patients admitted to the hospital with a diagnosis of SARS were studied. These patients were taken nasopharyngeal swabs were investigated by PCR for the detection of respiratory pathogens. A positive result was obtained with rhinovirus infection of 51 patients.</p></sec><sec><title>Results</title><p>Results. Of the examined patients, 41,6% had influenza, 45,8% had no viruses and 12,6% had other viral infections, of which 40% were due to rhinovirus infection. Among them, young patients prevailed: the median age for men was 31,0 years, for women-27,5 years. The disease occurred in a moderate form – 78,8%, severe course was observed in 5,3% of patients and was accompanied by infectious and toxic shock. Most often the disease occurred with complications acute bronchitis – 22,1%, pneumonia joined in 15,7% of cases.</p></sec><sec><title>Conclusion</title><p>Conclusion. rhinovirus infection ranks first (40%) among non-influenza causes of viral respiratory tract infection in the examined patients. It was registered mainly in young people. In most cases, it proceeded in a moderate form and had a complicated course, including pneumonia.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>клиника</kwd><kwd>осложнения</kwd><kwd>пневмония</kwd><kwd>риновирусы</kwd><kwd>эпидемиология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>clinic</kwd><kwd>complications</kwd><kwd>pneumonia</kwd><kwd>rhinoviruses</kwd><kwd>epidemiology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Осидак, Л.В. Острые респираторные инфекции : руководство для врачей / Л.В. Осидак. – СПб., 2014. – С. 110.</mixed-citation><mixed-citation xml:lang="en">Osidak L.V./ Acute respiratory infection / руководство для врачей guide for doctors SPb 2014 P 110</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">To KKW, Yip CCY, Yuen KY. 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