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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2020-12-3-12-20</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-1072</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальное исследование</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Течение новой коронавирусной инфекции у детей: некоторые аспекты мониторинга заболеваемости и анализа летальности</article-title><trans-title-group xml:lang="en"><trans-title>Course of a new coronavirus infection in children: some aspects of monitoring and analysis of mortality</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Uskov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Усков Александр Николаевич – заместитель директора по научной работе (по разработке и координации национальных и международных научных проектов), д.м.н, главный внештатный специалист ФМБА России по инфекционным болезням у детей</p><p>Санкт-Петербург; тел.: 8(812)346-22-02</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">aouskov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобзин</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobzin</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лобзин Юрий Владимирович – директор, д.м.н., профессор, академик РАН, заслуженный деятель науки РФ, главный внештатный специалист Минздрава России по инфекционным болезням у детей</p><p>Санкт-Петербург; тел.: 8(812) 234-60-04 </p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">niidi@niidi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рычкова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rychkova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рычкова Светлана Владиславовна – руководитель отдела организации медицинской помощи Детского научно-клинического центра инфекционных болезней, д.м.н. </p><p>Санкт-Петербург; тел.: 8(812)234-37-18, +7-921-310-65-81</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">rychkova.sv@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаченко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Babachenko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабаченко Ирина Владимировна – руководитель отдела респираторных (капельных) инфекций, д.м.н., профессор</p><p>Санкт-Петербург; тел.: 8(812)234-29-87</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">babachenko-doc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">fedorov.vv@niidi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Улуханова</surname><given-names>Л. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Ulukhanova</surname><given-names>L. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Улуханова Лала Уджаговна – заведующая кафедрой пропедевтики детских болезней с курсом детских инфекций, д.м.н., профессор</p><p>Махачкала; тел.: +7-928-950-77-43  </p></bio><bio xml:lang="en"><p>Makhachkala</p></bio><email xlink:type="simple">Lala.uluhanova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Починяева</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pochinyaeva</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Починяева Любовь Михайловна – заместитель главного врача, к.м.н. </p><p>Санкт-Петербург; тел.: 8(812)400-04-11</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">expert@db5.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Детский научно-клинический центр инфекционных болезней<country>Россия</country></aff><aff xml:lang="en">Pediatric Research and Clinical Center for Infections Diseases<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Дагестанский государственный медицинский университет<country>Россия</country></aff><aff xml:lang="en">Dagestan state medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Детская городская клиническая больница № 5 им Н.Ф. Филатова<country>Россия</country></aff><aff xml:lang="en">Сhildren’s City Clinical Hospital № 5 named after N. F. Filatov<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>30</day><month>07</month><year>2020</year></pub-date><volume>12</volume><issue>3</issue><fpage>12</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Усков А.Н., Лобзин Ю.В., Рычкова С.В., Бабаченко И.В., Федоров В.В., Улуханова Л.У., Починяева Л.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Усков А.Н., Лобзин Ю.В., Рычкова С.В., Бабаченко И.В., Федоров В.В., Улуханова Л.У., Починяева Л.М.</copyright-holder><copyright-holder xml:lang="en">Uskov A.N., Lobzin Y.V., Rychkova S.V., Babachenko I.V., Fedorov V.V., Ulukhanova L.U., Pochinyaeva L.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/1072">https://journal.niidi.ru/jofin/article/view/1072</self-uri><abstract><p>Цель: провести анализ существующего в РФ мониторинга заболеваемости детей новой коронавирусной инфекцией и особенностей летальных случаев COVID-19 у детей. Материалы и методы: в период с 22.04.2020 г. по 26.06.2020 г. проведен анализ данных оперативной статистики на сайтах правительств регионов, в которых учитывали заболеваемость детей, а также данные главных внештатных специалистов по инфекционным болезням у детей. Проанализированы медицинские карты стационарных больных и данные патолого-анатомического исследования детей, погибших от COVID-19. Результаты. Распространенность COVID-19 у детей в различных регионах РФ составляла от 1% до 8,6% в структуре общей заболеваемости. Бессимптомные и легкие формы болезни, не требовавшие госпитализации, отмечали в 55–60% случаев. На 22.06.2020 г. было зарегистрировано 12 летальных случаев, ассоциированных с COVID-19. Анализ 8 представленных случаев показал, что из 8 погибших детей 6 человек были первого полугодия жизни (3 девочки и 5 мальчиков). В большинстве случаев дети поступали в стационар на 8–12-й дни заболевания в тяжелом и крайне тяжелом состоянии за счет легочносердечной недостаточности, 6 – с лихорадкой до 38–39°С, 4 – с признаками угнетения сознания. У всех детей по данным рентгенографии, ультразвукового исследования или компьютерной томографии органов грудной клетки диагностировали внебольничную двустороннюю пневмонию, что не всегда совпадало с выраженностью респираторного синдрома. Непосредственной причиной смерти явилась сердечная или легочно-сердечная недостаточность. Заключение. Анализ клинических и лабораторных проявлений COVID-19 с неблагоприятным исходом у детей выявил сложности в интерпретации ее роли в танатогенезе. Несомненным является значение коморбидной патологии в развитии неблагоприятных исходов.</p></abstract><trans-abstract xml:lang="en"><p>The work objective was to carry out the analysis of the existing in the Russian Federation monitoring of the incidence of new coronavirus infection in children and specific features of death cases caused by COVID-19 in children. Materials and methods. The analysis of the data of operative statistics presented on the sites of the governments of the regions where the incidence among children was considered within the period from April 22, 2020 to June 26, 2020, as well as the data of the Main non-staff experts in infectious diseases in children was performed. The inpatient medical documentation and the data of pathologicoanatomic investigation of children died due to COVID-19 were analyzed. Results. Prevalence of COVID-19 in children from various regions of the Russian Federation was from 1% to 8.6% in the structure of general disease incidence. The asymptomatic and mild forms of the disease which did not require hospitalization, were noted in 55–60% of the cases. 12 death cases associated with COVID-19 were registered for June 22, 2020. The analysis of 8 presented cases showed that 6 patients out of 8 died children were of the first half of the year of life (3 girls and 5 boys). In most cases the children were admitted to the hospital at the 8–12th day of the disease in severe and extremely severe condition due to pulmonary-cardiac insufficiency, six patients had fever up to 38–39°С, four patients had signs of consciousness depression. All children were diagnosed with community-acquired bilateral pneumonia according to the data of roentgenography, ultrasound investigation or computer tomography of the chest organs that did not always coincide with the intensity of respiratory syndrome. The direct cause of death was cardiac or pulmonary-cardiac insufficiency. Conclusion. The analysis of clinical and laboratory manifestations of COVID-19 with an unfavourable outcome in children revealed some difficulties in the interpretation of its role in thanatogenesis. The significance of comorbid pathologies in the development of unfavourable outcomes is doubtless.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>новая коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>дети</kwd><kwd>мониторинг</kwd><kwd>летальность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>new coronavirus infection</kwd><kwd>COVID 19</kwd><kwd>children</kwd><kwd>monitoring</kwd><kwd>death cases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вирусы и вирусные инфекции : руководство по вирусологии / под ред. Д.К. Львова – М.: МИА, 2013. – С. 211–217.</mixed-citation><mixed-citation xml:lang="en">Viruses and viral infections. Virology Guide / red D.K. 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